Direct, Late-Stage Mono-N-arylation of Pentamidine: Method Development, Mechanistic Insight, and Expedient Access to Novel Antiparastitics against Diamidine-Resistant Parasites.

Publication Year: 2021

DOI:
10.1002/cmdc.202100509

PMCID:
PMC9291547

PMID:
34357687

Journal Information

Full Title: ChemMedChem

Abbreviation: ChemMedChem

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Pharmacology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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"Conflict of interest The authors declare no conflict of interest."

Evidence found in paper:

"J.R. and G.A.B. thank GlaxoSmithKline (GSK) and the Engineering and Physical Sciences Research Council (EPSRC) for an industrial CASE studentship (EP/P51066X/1). MMA is supported by a studentship from the government of Libya, and MAU by a studentship from the Petroleum Technology Development Fund (PTDF), Abuja, Nigeria. We thank Dr Alan Kennedy (University of Strathclyde) and Dr Nicola Bell (University of Glasgow) for assistance in the analysis of crystal structures."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025