Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses.

"Conflict of interest The authors declare no conflict of interest."

"This work was supported by the Ministero dell′Istruzione, dell′Università della Ricerca Italiano (MIUR) (PRIN 2017 project N. 2017BMK8JR, “ORIGINALE CHEMIAE in Antiviral Strategy – Origin and Modernization of Multi‐Component Chemistry as a Source of Innovative Broad Spectrum Antiviral Strategy” to M.R. and M.Z.). This work was also supported by a research grants from the European Union (Horizon 2020 Marie Skłodowska‐Curie ETN “ANTIVIRALS”, grant agreement number 642434 to F.J.M.v.K.), by the Italian Cancer Research Association (MFAG2016 18811 and IG 2020 ID 24448 to E.C.; IG2017‐20762 to G.M.) and by MIUR (PRIN 2017 project N. 2017SA5837 to G.M.). We thank Simona De Pasquale for excellent technical assistance. Open Access Funding provided by Universita degli Studi di Parma within the CRUI‐CARE Agreement."