Dual Antiplatelet Therapy Using Cilostazol With Aspirin or Clopidogrel: Subanalysis of the CSPS.com Trial.

"Disclosures Dr Hoshino reports personal fees from Daiichi-Sankyo and Pfizer outside the submitted work. Dr Toyoda reports personal fees from Daiichi-Sankyo, Bayer, Bristol-Myers-Squibb, Boehringer-Ingelheim, and Takeda, outside the submitted work. Dr Uchiyama reports receiving grant support, honoraria, advisory board fees, and lecture fees from Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Daiichi Sankyo, Takeda, Healios, Otsuka, and Sanofi. Dr Kimura received lecture fees from Bristol-Myers Squibb, Boehringer Ingelheim, Bayer, and Daiichi Sankyo and research funding from Boehringer Ingelheim, Daiichi Sankyo, Pfizer, Medtronic, and Teijin Pharma. Dr Sakai reports receiving grant support and lecture fees from Asahi-Intec, Daiichi Sankyo, Medtronic, NeuroVasc, Stryker, and Terumo. Dr Houkin reports receiving honoraria as principle investigator of a clinical trial from Healios. Dr Yamaguchi reports receiving lecture fee from Daiichi Sankyo. Dr Minematsu reports receiving honoraria from Bayer, Bristol-Myers Squibb, CSL Behring, Daiichi Sankyo, EPS Corporation, Fuji Film Pharma, Healios, Mitsubishi Tanabe, Nippon Chemiphar, Otsuka, Pfizer, Sanofi, and Stryker. Dr Terayama reports receiving grant support, consulting fees, and honoraria from Boehringer Ingelheim, Bristol-Myers Squibb, and Daiichi Sankyo. Dr Yasuda reports receiving grant support, lecture fees, and clinical trial fees from Abbott, Bristol-Myers Squibb, Daiichi Sankyo, and Takeda. Dr Yamaguchi reported personal fees from Daiichi-Sankyo and Pfizer outside the submitted work. The other authors report no conflicts."

"Sources of Funding CSPS.com (PI: Dr Yamaguchi) was conducted under a trial contract between the consignee, Japan Cardiovascular Research Foundation, and the consignor, Otsuka Pharmaceutical Co, Ltd. Japan Cardiovascular Research Foundation received funding for trial implementation and management from Otsuka Pharmaceutical Co, Ltd. Otsuka Pharmaceutical Co, Ltd, did not directly contribute to trial design, data management, or statistical analysis and did not contribute to any issues on this subanalysis study. Statistical analysis of this article was performed in the Department of Data Science, National Cerebral and Cardiovascular Center (Omae, Ishida). This study was funded mainly by the Japan Agency for Medical Research and Development to Toyoda K (AMED, 20lk0201094h0002, and 20lk0201109h0001)."

"Registration:: URL: https://www.clinicaltrials.gov; Unique identifier: NCT01995370. URL: https://www.umin.ac.jp/ctr/; Unique identifier: UMIN000012180."