Adapting the ACMG/AMP variant classification framework: A perspective from the ClinGen Hemoglobinopathy Variant Curation Expert Panel.

Publication Year: 2021

DOI:
10.1002/humu.24280

PMCID:
PMC9545675

PMID:
34510646

Journal Information

Full Title: Hum Mutat

Abbreviation: Hum Mutat

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics, Medical

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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"CONFLICT OF INTERESTS The authors declare that there are no conflict of interests."

Evidence found in paper:

"We are grateful to Helen Merrideth Robinson for her pioneering liaison efforts critical to establishing the Hemoglobinopathy VCEP, and to Sir John Burn for ongoing advice and support as Executive Chairman of the Human Variome Project. We also thank Steven M. Harrison, Leslie G. Biesecker, and the ClinGen SVI WG for reviewing the specified VCEP rules and for providing valuable feedback. This study is co‐funded by the European Regional Development Fund and the Republic of Cyprus through the Research and Innovation Foundation (Project: EXCELLENCE/1216/256)."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025