Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice.

"microarray data have been submitted to ncbi/geo ( gse148227 ) scrna-seq data have been submitted to ncbi/geo ( gse147319 ). supplementary data 1 source data for supplementary fig 2. data availability all data generated or analysed during this study are included in this article and its supplementary files. microarray data have been submitted to ncbi/geo ( gse148227"

"code availability code and custom scripts for scrna-seq analysis have been deposited on https://github com/theislab/2021_aliluev_tritschler_gut_hfd ."

"Competing interests M.H.T. serves as a scientific advisory board member of ERX Pharmaceuticals, Inc, Cambridge, MA. F.J.T. reports receiving consulting fees from Cellarity, Inc and ownership interest in Cellarity, Inc. and Dermagnostix. S.T. is an employee of Cellarity, Inc. and has stake-holder interests; the present work was carried out as an employee of Helmholtz Munich. The remaining authors declare no competing interests."

"Funding Open access funding provided by Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (4209)."