Protein Nutritional Status and Frailty: A Mendelian Randomization Study.

"for data on the association between genetic variants and serum proteins we used gwas summary statistics from the uk biobank (regression coefficients for serum proteins in g/l) released by the neale lab ( https://github com/nealelab/uk_biobank_gwas )."

"for data on the association between genetic variants and serum proteins we used gwas summary statistics from the uk biobank (regression coefficients for serum proteins in g/l) released by the neale lab ( https://github com/nealelab/uk_biobank_gwas )."

"Notes: Supported by the Swedish Research Council (grant numbers 2018-02077 and 2019-01272), the Loo & Hans Osterman Foundation, the Strategic Research Program in Epidemiology at Karolinska Institute, and the King Gustaf V and Queen Victoria Freemason Foundation.: Author disclosure: All authors report no conflict of interests.: Supplemental Figure 1 and Supplemental Tables 1–6 are available from the “Supplementary data” link in the online posting of the article and from the same link in the online table of contents at https://academic.oup.com/jn/.: Abbreviations used: FI, frailty index; GWAS, genome-wide association study; MR, Mendelian randomization; RCT, randomized controlled trial."

"We thank all the technical assistance at Karolinska Institute, especially Bowen Tang and Tatsuya Yagi. We thank the UK Biobank participants and the UK Biobank for making the data available. This research has been conducted using the UK Biobank Resource under application number 22224. The analyses of UK Biobank genotypes were enabled by resources provided by the Swedish National Infrastructure for Computing (SNIC) at Uppmax, partially funded by the Swedish Research Council through grant agreement number 2018–05973. Notes: Supported by the Swedish Research Council (grant numbers 2018-02077 and 2019-01272), the Loo & Hans Osterman Foundation, the Strategic Research Program in Epidemiology at Karolinska Institute, and the King Gustaf V and Queen Victoria Freemason Foundation.: Author disclosure: All authors report no conflict of interests.: Supplemental Figure 1 and Supplemental Tables 1–6 are available from the “Supplementary data” link in the online posting of the article and from the same link in the online table of contents at https://academic.oup.com/jn/.: Abbreviations used: FI, frailty index; GWAS, genome-wide association study; MR, Mendelian randomization; RCT, randomized controlled trial."