Worldwide post-marketing safety surveillance experience with tofacitinib in ulcerative colitis.

"Declaration of personal interests: David T. Rubin has received grant support from Takeda; and has served as a consultant for AbbVie, AbGenomics, Allergan Inc, Boehringer Ingelheim, Bristol‐Myers Squibb, Celgene Corp/Syneos, Check‐cap, Dizal Pharmaceuticals, Eli Lilly, GalenPharma/Atlantica, Genentech/Roche, Gilead Sciences, GSK, Ichnos Sciences S.A, Janssen, Narrow River Management, Pfizer Inc, Prometheus Laboratories, Reistone, Shire, Takeda, and Techlab Inc. Séverine Vermeire has received grant support from AbbVie, MSD, Pfizer Inc, and Takeda; served as a speaker for AbbVie, Dr. Falk Pharma, Ferring, Hospira, MSD, Takeda, and Tillotts; and served as a consultant for AbbVie, Celgene, Ferring, Galapagos, Genentech/Roche, Hospira, Janssen, MSD, Mundipharma, Pfizer Inc, Second Genome, Shire, and Takeda. Silvio Danese has served as a consultant for AbbVie, Allergan, Amgen, AstraZeneca, Biogen, Boehringer Ingelheim, Celgene, Celltrion, Ferring, Gilead Sciences, Hospira, Janssen, Johnson & Johnson, MSD, Mundipharma, Pfizer Inc, Roche, Sandoz, Takeda, TiGenix, UCB, and Vifor. Siew C. Ng has received research grant support from AbbVie, Ferring, and Olympus; served as a speaker for AbbVie, Ferring, Janssen, Menarini, and Takeda; and holds a directorship with Microbiota I Center. Irene Modesto, Kenneth K. Kwok, Nana Koram, and Thomas V. Jones are employees of Pfizer Inc. Irene Modesto, Kenneth K. Kwok, Nana Koram, and Thomas V. Jones own stocks and shares in Pfizer Inc."

"This study was sponsored by Pfizer Inc. The authors thank the patients, investigators and study teams involved in OCTAVE Induction 1 and 2. This work was supported by Pfizer Inc. Writing support, under the guidance of the authors, was provided by Helen Findlow, PhD, CMC Connect, McCann Health Medical Communications and was funded by Pfizer Inc, New York, NY, USA in accordance with Good Publication Practice (GPP3) guidelines (Ann Intern Med 2015;163:461–464). Declaration of personal interests: David T. Rubin has received grant support from Takeda; and has served as a consultant for AbbVie, AbGenomics, Allergan Inc, Boehringer Ingelheim, Bristol‐Myers Squibb, Celgene Corp/Syneos, Check‐cap, Dizal Pharmaceuticals, Eli Lilly, GalenPharma/Atlantica, Genentech/Roche, Gilead Sciences, GSK, Ichnos Sciences S.A, Janssen, Narrow River Management, Pfizer Inc, Prometheus Laboratories, Reistone, Shire, Takeda, and Techlab Inc. Séverine Vermeire has received grant support from AbbVie, MSD, Pfizer Inc, and Takeda; served as a speaker for AbbVie, Dr. Falk Pharma, Ferring, Hospira, MSD, Takeda, and Tillotts; and served as a consultant for AbbVie, Celgene, Ferring, Galapagos, Genentech/Roche, Hospira, Janssen, MSD, Mundipharma, Pfizer Inc, Second Genome, Shire, and Takeda. Silvio Danese has served as a consultant for AbbVie, Allergan, Amgen, AstraZeneca, Biogen, Boehringer Ingelheim, Celgene, Celltrion, Ferring, Gilead Sciences, Hospira, Janssen, Johnson & Johnson, MSD, Mundipharma, Pfizer Inc, Roche, Sandoz, Takeda, TiGenix, UCB, and Vifor. Siew C. Ng has received research grant support from AbbVie, Ferring, and Olympus; served as a speaker for AbbVie, Ferring, Janssen, Menarini, and Takeda; and holds a directorship with Microbiota I Center. Irene Modesto, Kenneth K. Kwok, Nana Koram, and Thomas V. Jones are employees of Pfizer Inc. Irene Modesto, Kenneth K. Kwok, Nana Koram, and Thomas V. Jones own stocks and shares in Pfizer Inc."