Unique functions for Notch4 in murine embryonic lymphangiogenesis.

"the rnaseq datasets generated in the current study are available in the ncbi gene expression omnibus repository at https://www ncbi nlm nih gov/geo (accession number gse183631)."

"Declarations Conflict of interestJan Kitajewski has received research funding from Eisai Pharmaceuticals (CU12-3625 and UICID#084028 Eisai Ltd. Research Collaborative Agreements). All other authors declare that they have no conflict of interests. Ethical approvalIsolation of HUVEC and HdLEC from anonymous discarded specimens and received IRB exempt status by Columbia University IRB (AAAA7338). All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Mouse studies were approved by Columbia University IACUC (AC-AAAE2653, AC-AAAD0577, AC-AAAP9603, AC-AAAP0452, AC-AABB9551). All procedures performed in studies involving animals were in accordance with the ethical standards of the institution or practice at which the studies were conducted. Conflict of interest Jan Kitajewski has received research funding from Eisai Pharmaceuticals (CU12-3625 and UICID#084028 Eisai Ltd. Research Collaborative Agreements). All other authors declare that they have no conflict of interests."

"Funding This study was funded by the NIH/NCI (R01CA136673; CJS, JKK), NIH/NIDDK (R01 R01DK107633; CJS), NIH/NHLBI (RO1HL112626; JKK), the DOD pre-doctoral fellowship (W81XWH-10-1-0304; MKU), and the Lipedema Foundation (CJS). These studies used the resources of the Herbert Irving Comprehensive Cancer Center Flow Cytometry Shared Resources funded in part through Center Grant P30CA013696."