Fasting Concentrations and Postprandial Response of 1,2-Dicarbonyl Compounds 3-Deoxyglucosone, Glyoxal, and Methylglyoxal Are Not Increased in Healthy Older Adults.

"Conflict of Interest None declared."

"Funding This work was supported by the Deutsche Forschungsgemeinschaft (RA 3524/2-1 to J.R.)."

"This is a secondary analysis of a larger study which is described in detail elsewhere (). In brief, the study was performed in community-dwelling older (65–85 years) and younger adults (18–35 years). Exclusion criteria were type 1 and 2 diabetes, a stroke or heart attack in the past 6 months, food allergies and intolerances, pregnancy, or any severe or malignant disease. The study was approved by the ethics committee of the University of Potsdam and registered at drks.de as DRKS00017090. All participants signed a written informed consent. In this study, 19 older (OW) and younger women (YW), as well as 15 older (OM) and younger men (YM), were included in the analyses. From these participants, blood samples after an oral dextrose challenge were available in n = 14 OW, n = 10 YW, n = 5 OM, and n = 5 YM."