Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person.

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationThe authors declare that they agree with the publication. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding Open Access funding enabled and organized by Projekt DEAL. Open Access funding enabled and organized by Projekt DEAL. The present study was supported by the Scientific Grant Agency of the Ministry of Education, Science, Research and Sport of the Slovak Republic (Bratislava, Slovak Republic; grant no. VEGA 1/0136/19), Slovak Research and Development Agency under Contract No. APVV-16–0021, and by the LISPER project (grant Nr. 313011V446) in bilateral agreement with the European Association for Predictive, Preventive and Personalised Medicine."