Aquaporin 9 induction in human iPSC-derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency.

Authors:
Laemmle A; Poms M; Hsu B; Borsuk M; Rüfenacht V and 5 more

Journal:
Hepatology

Publication Year: 2021

DOI:
10.1002/hep.32247

PMCID:
PMC9295321

PMID:
34786702

View on PubMed View on PMC View Publisher
Journal Information

Full Title: Hepatology

Abbreviation: Hepatology

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Gastroenterology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Related Papers from Same Journal
A global action agenda for turning the tide on fatty liver disease.
Lazarus JV; Mark HE; Allen AM and 44 more (2023) - Transparency Score: 3/6
c-Rel-dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis.
Leslie J; Hunter JE; Collins A and 15 more (2023) - Transparency Score: 3/6
Effect of tenofovir-based HIV pre-exposure prophylaxis against HBV infection in men who have sex wi…
Mizushima D; Takano M; Aoki T and 7 more (2023) - Transparency Score: 3/6
Emergence of resistance-associated variants during sofosbuvir treatment in chronically infected hep…
Gömer A; Klöhn M; Jagst M and 12 more (2023) - Transparency Score: 3/6
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression.
Juárez-Fernández M; Goikoetxea-Usandizaga N; Goikoetxea-Usandizaga N and 18 more (2023) - Transparency Score: 4/6
View All Papers from This Journal
Transparency Score
4/6
66.7% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Evidence found in paper:

"a microarray data set previously published by bonder et al [ ] deposited in the national center for biotechnology information gene expression omnibus (geo) database under accession number gse61279 was analyzed for relative mrna expression of aqp9 and other enzymes and transporters involved in ammonia detoxification and urea metabolism in fetal and adult human liver tissue."

Code Sharing
Evidence found in paper:

"CONFLICT OF INTEREST Dr. Willenbring advises and owns stock in Ambys."

Evidence found in paper:

"Funding information"

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025