Accuracy of H. pylori fecal antigen test using fecal immunochemical test (FIT).

"Declarations Conflict of interestSAVN declares that she has no conflict of interest. MCM declares that he has no conflict of interest. LMMW declares that she has no conflict of interest. AJV declares that she has no conflict of interest. NE declares that she has no conflict of interest. MPP declares that he has no conflict of interest. GMF declares that she has no conflict of interest. MJB has received research grants from Boston Scientific, grants and personal fees from Cook Medical, grants from Pentax Medical, grants from 3M, grants from Mylan, grants from InterScope, outside the submitted work. EJK declares that he has no conflict of interest. MCWS has received grants from sysmex, sentinel, Medtronic, Boston Scientific, Norgine, outside the submitted work. Ethical statementAll procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. Informed consent to be included in the study, or the equivalent, was obtained from all patients. Conflict of interest SAVN declares that she has no conflict of interest. MCM declares that he has no conflict of interest. LMMW declares that she has no conflict of interest. AJV declares that she has no conflict of interest. NE declares that she has no conflict of interest. MPP declares that he has no conflict of interest. GMF declares that she has no conflict of interest. MJB has received research grants from Boston Scientific, grants and personal fees from Cook Medical, grants from Pentax Medical, grants from 3M, grants from Mylan, grants from InterScope, outside the submitted work. EJK declares that he has no conflict of interest. MCWS has received grants from sysmex, sentinel, Medtronic, Boston Scientific, Norgine, outside the submitted work."

"The authors would like to acknowledge B.H.C.M. Roovers, J. Francke, M. Ouwendijk and F. van Deurzen for their assistance in the execution of the tests in the Erasmus MC. We would also like to acknowledge A. van Liere-Baron for her assistance in organizational tasks and logistics at the Albert Schweitzer Hospital. This study was supported by the Dutch Digestive Foundation (D18-02)."

"This prospective study was performed in two hospitals (one academic and one regional) in the Netherlands. Patients were eligible for inclusion if they were over 18 years of age and were referred for UBT at the general practitioner’s discretion. They were identified through the outpatient clinic of the participating hospitals and contacted by telephone. After informed consent, patients were sent a first questionnaire and feces sampling kits with instructions. Patients were excluded if they had used antibiotics/bismuth in the past 4 weeks, or a proton pump inhibitor (PPI) in the past 2 weeks. All participants underwent UBT, SAT, Hp-FIT and blood sampling. Patient inclusion took place between February 2018 and December 2020. UBT results were used as reference. The performers of the SAT, Hp-FIT and blood sampling were blinded to the UBT results. The institutional review boards of both participating hospitals approved the study (MEC-2017-528). This trial was registered in the Dutch trial register (NTR7052). All co-authors had access to the study data and had reviewed and approved the final manuscript."