Dissecting the IL-6 pathway in cardiometabolic disease: A Mendelian randomization study on both IL6 and IL6R.

"a list of the data sources and r code is enclosed in the supplemental materials."

"COMPETING INTERESTS A.J.C. has nothing to disclose. F.W.A. and A.F.S. have received Servier funding for unrelated work. P.N. has received research support from Apple, Amgen and Boston Scientific, personal fees from Apple, Genentech, Novartis and Blackstone Life Sciences, and spousal employment at Vertex, all unrelated to the present work. P.M.R. has served as a consultant to Flame, Agepha, Corvidia, Inflammazome, Novartis, Amgen, Merck and Civi Bio and is listed as co‐inventor on patents related to the use of inflammatory biomarkers in CVD and diabetes that are no longer active. G.K.H. has received funding from Regeneron, Aegerion, Amgen, AstraZeneca, Eli Lilly, Genzyme, Kowa, Pfizer, Regeneron Pharmaceuticals, Roche, Sanofi, The Medicines Company, Ionis and personal fees from Novo Nordisk."

"A.J.C. is supported by grants from the Atheros fund and the AMC Young Talent Fund. F.W.A. is supported by UCL Hospitals NIHR Biomedical Research Centre. P.N. is supported by grants from the National Heart, Lung, and Blood Institute (R01HL142711, R01HL148565, R01HL148050, R01HL151283), Fondation Leducq (TNE‐18CVD04), and Hassenfeld Scholar Award from the Massachusetts General Hospital. P.M.R. has received investigator‐initiated research grants from Kowa, Novartis, Pfizer, AstraZeneca, NHLBI and NCI. G.K.H. is supported by grants from Netherlands Organization for Scientific Research, grants from Klinkerpad fonds, and grants from the European Union. A.F.S. is supported by BHF grant PG/18/5033837 and the UCL BHF Research Accelerator AA/18/6/34223."