Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials.

Authors:
Wang G; Mohanty B; Williams ML; Doak BC; Dhouib R and 10 more

Journal:
ChemMedChem

Publication Year: 2022

DOI:
10.1002/cmdc.202100673

PMCID:
PMC9305425

PMID:
34978144

Journal Information

Full Title: ChemMedChem

Abbreviation: ChemMedChem

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Pharmacology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"crystal structures of the ecdsba-tc complex and the vcdsba-tc complexes have been deposited into the protein data bank with codes7lui and 7lsm respectively."

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"Conflict of interest The authors declare no conflict of interest."

Evidence found in paper:

"This work was supported by the National Health and Medical Research Council (NHMRC) (Project Grants 1099151 & 1144046) and the Australian Research Council (ARC) (Industry Transformation Training Centre Grant IC180100021). Dr. Begoña Heras was supported by an ARC Future Fellowship (FT130100580). Martin Williams was the recipient of an Australian Postgraduate Award. We would like to acknowledge the La Trobe University‐Comprehensive Proteomics Platform and the Monash Fragment Platform (MFP) for providing infrastructure and expertise. This research was undertaken using the MX1, MX2 beamlines at the Australian Synchrotron, part of ANSTO. Some of the NMR data were acquired at the NMR Facility of Bio21. Open access publishing facilitated by Monash University, as part of the Wiley ‐ Monash University agreement via the Council of Australian University Librarians."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025