An International Multicenter Study Exploring Whether Surveillance After Esophageal Cancer Surgery Impacts Oncological and Quality of Life Outcomes (ENSURE).

"The authors report no conflicts of interest."

"Funding: Supported by a fellowship award from the Health Research Board, Ireland, to Jessie A Elliott (HPF 2015-1013) and a grant award from the Surgical Research Society, United Kingdom and Ireland."

"The study was registered on ClinicalTrials.gov before inclusion of the first participant (NCT03461341), and was registered with the Research and Innovation Hub, St. James’s Hospital, Dublin, Ireland (approval number #4982) and approved by the St. James’s Hospital and Tallaght University Hospital Joint Research Ethics Committee (approval number #2018-08-CA). Local approvals were obtained in accordance with national policy in participating countries. The study was conducted in compliance with the principles of the Declaration of Helsinki (1996), the principles of Good Clinical Practice and in accordance with all applicable regulatory requirements including but not limited to the Research Governance Framework and the Medicines for Human Use (Clinical Trial) Regulations 2004, as amended in 2006 and any subsequent amendments. This study is reported in accordance with the STrengthening the Reporting of OBservational studies in Epidemiology guidelines."