AI-Driven Model for Automatic Emphysema Detection in Low-Dose Computed Tomography Using Disease-Specific Augmentation.

"Declarations Ethics ApprovalApproved by Institutional Review Board–the Medical Ethical Committee (METc) of the University Medical Center Groningen. Informed ConsentWritten informed consent was obtained from all subjects of the ImaLife and NLST study. Study Subjects or Cohorts OverlapThe details of eligibility criteria for the participants of ImaLife and National Lung Cancer screening (NLST) have been previously described. There was no-overlap of study subjects or cohorts. Statistics and BiometryOne of the authors has significant statistical expertise. Conflict of InterestProf. Dr. Rozemarijn Vliegenthart reports an institutional research grant from Siemens Healthineers. There are no other interests to disclose. Rest of the authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. Conflict of Interest Prof. Dr. Rozemarijn Vliegenthart reports an institutional research grant from Siemens Healthineers. There are no other interests to disclose. Rest of the authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article."

"Funding Part of this work was realized within the Imaging in Lifelines (ImaLife) study supported by the institutional research grant from the Siemens Healthineers and by the Ministry of Economic Affairs and Climate Policy (EZK) by means of the public–private partnership (PPP) allowance made available by the Top Sector Life Sciences and Health to stimulate public–private partnerships. Part of this work was realized within the Deep Learning Algorithms for Medical Image Evaluation (DAME) project, funded by the INTERREG V. A Germany-Netherlands program with resources from the European Regional Development Fund and co-funded by the Netherlands Ministry of Economic Affairs and Climate Policy (EZK), the Province of Groningen and the Niedersächsisches Ministerium für Bundes-und Europaangelegenheiten und Regionale Entwicklung."