Association Between Acid-Suppressive Agents' Use and Risk of Hepatocellular Carcinoma.

"Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article."

"Funding: The author(s) received no financial support for the research, authorship, and/or publication of this article."

"The Longitudinal Health Insurance Database 2000 (LHID2000), one of the data subsets of the National Health Insurance (NHI) Research Database (NHIRD), was used to conduct a population-based retrospective nationwide cohort study. The NHIRD is a large computerized database derived from the nationwide NHI program in Taiwan and is maintained by the National Health Research Institutes (NHRI) for research purposes. There are approximately 23.75 million individuals in the NHIRD, which contains the original registration and claims data for reimbursement of the single-payer NHI program, and 1 million individuals randomly sampled from the 2000 Registry for Beneficiaries (ID) constitute the LHID2000. There was no significant difference in the number of birth per year, the age distribution, or the gender distribution between patients in the LHID2000 and the original NHIRD."