Non-clinical immunogenicity, biodistribution and toxicology evaluation of a chimpanzee adenovirus-based COVID-19 vaccine in rat and rhesus macaque.

Authors:
Dai X; Zhao W; Tong X; Liu W; Zeng X and 6 more

Journal:
Arch Toxicol

Publication Year: 2022

DOI:
10.1007/s00204-021-03221-x

PMCID:
PMC8883008

PMID:
35226134

Journal Information

Full Title: Arch Toxicol

Abbreviation: Arch Toxicol

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Toxicology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"Declarations Conflicts of interestThe authors declare that they have no conflict of interest. Compliance with ethical standardsAll animal experiment protocols were reviewed and approved by the Institutional Animal Care and Use Committee of Center for New Drug Safety Evaluation and Research, China Pharmaceutical University. Conflicts of interest The authors declare that they have no conflict of interest."

Evidence found in paper:

"Funding This work was funded by Yunnan Walvax Biotech, Co. LTD."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
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Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025