Anti-phospholipid antibodies are elevated and functionally active in chronic rhinosinusitis with nasal polyps.

"CONFLICT OF INTEREST Robert C. Kern is a consultant of Lyra Therapeutics, Sanofi Regeneron, GlaxoSmithKline, and Genentech. Anju T. Peters reports personal fees from Sanofi Regeneron, grants and personal fees from AstraZeneca and Optinose, outside the submitted work. Leslie C. Grammar III has received grants from the National Institutes of Health and Bazley Foundation to support her research. She has received grants for the institution from the National Institute of Health Food Allergy Network, AstraZeneca, and Sanofi Regeneron. She is a consultant for Astellas Pharmaceuticals. She has received royalties and payment for lectures from the American Academy of Allergy, Asthma and Immunology (AAAAI), Mount Sinai, Lippincott, UpToDate, Elsevier, Kluwers Wolter. Whitney W. Stevens has served on an advisory board for GlaxoSmithKline. Robert P. Schleimer is a consultant for Intersect ENT, GlaxoSmithKline, Merck, Sanofi, AstraZeneca/Medimmune, Genentech, Otsuka, Actobio Therapeutics, Lyra Therapeutics, Astellas Pharm Inc, Genzyme/Sanofi Corp, and Celgene Corp. He is also a consultant with stock/stock options with Allakos, Aurasense, BioMarck, Exicure, and Aqualung Therapeutics Corp. He has a patent with Allakos related to Siglec‐8 and Siglec‐8 ligand related products that have not been developed yet. He has also received grants from the National Institutes of Health to support this and other research. Bruce K. Tan has received grants from the National Institutes of Health to support this research. He has served on advisory boards for Sanofi/Genzyme. All other authors have no conflicts of interest to report."

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