Free Cholesterol Bioavailability and Atherosclerosis.

"Declarations Human and Animal Rights and Informed Consent.This article does not contain any studies with human or animal subjects performed by any of the authors. Conflict of InterestLF reports the following patents planned, issued, or pending: (1) Compositions and methods for regulating angiogenesis and cholesterol and treating dyslipidemia, atherosclerosis, cancer, and inflammatory conditions (US20160115211A1); (2) compositions and methods for increasing lymphangiogenesis (Attorney Docket Number 10063-057WO1); (3) compositions and methods for treating neovascularization and ischemic retinopathies by targeting angiogenesis and cholesterol transport; and (4) Methods and compositions for treatment of aberrant hematopoiesis (Attorney Docket No. 16315-P002WO).JPC reports consulting fees from JanOne.The other authors declare that they have no conflict of interest. Conflict of Interest LF reports the following patents planned, issued, or pending: (1) Compositions and methods for regulating angiogenesis and cholesterol and treating dyslipidemia, atherosclerosis, cancer, and inflammatory conditions (US20160115211A1); (2) compositions and methods for increasing lymphangiogenesis (Attorney Docket Number 10063-057WO1); (3) compositions and methods for treating neovascularization and ischemic retinopathies by targeting angiogenesis and cholesterol transport; and (4) Methods and compositions for treatment of aberrant hematopoiesis (Attorney Docket No. 16315-P002WO). JPC reports consulting fees from JanOne. The other authors declare that they have no conflict of interest."

"Funding This work was supported in part by grants to JPC (NHLBI R01HL133254), LF (NHLBI R01HL132155), EAD (NIAMS R21AR077783 and DOD PR200305), and NTL (NHLBI R01HL134740)."