Structure-Based Virtual Screening and in vitro and in vivo Analyses Revealed Potent Methyltransferase G9a Inhibitors as Prospective Anti-Alzheimer's Agents.

"Conflict of interest The authors declare no conflict of interest."

"B.S.C. and S. are grateful to Council for Scientific and Industrial Research, India, for Senior Research Fellowship (Grant No. 09/1131(0004)/2016‐EMR‐I and 09/1131(0026)/2019‐EMR‐I) and Central University of Rajasthan for providing computational facilities. A.B‐S acknowledge the Agència de Gestió d′Ajuts Universitaris i de Recerca (AGAUR) for her FI‐SDUR fellowship (2021 FISDU 00182). J.C‐A acknowledge the Ministry of Economy and Competitiveness (MINECO) for her FPI fellowship (MDM‐2017‐0729‐19‐2). C. elegans strains were provided by the Caenorhabditis Genetics Center (CGC), which is funded by NIH Office of Research Infrastructure Programs (P40 OD010440). We thank Gemma Triola from the Institute of Advanced Chemistry of Catalonia (IQAC‐CSIC) and her lab for offering the possibility of using the AlphaScreen microplate reader."