Cell-line dependency in cerebral organoid induction: cautionary observations in Alzheimer's disease patient-derived induced pluripotent stem cells.

Authors:
Lee JH; Yoo G; Choi J; Park SH; Shin H and 5 more

Journal:
Mol Brain

Publication Year: 2022

DOI:
10.1186/s13041-022-00928-5

PMCID:
PMC9109296

PMID:
35578344

Journal Information

Full Title: Mol Brain

Abbreviation: Mol Brain

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Molecular Biology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"Declarations Ethics approval and consent to participateAll experimental procedures involving human iPSCs were approved by the Institutional Review Board of Korea University. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

Evidence found in paper:

"Funding This research was supported by the Brain Research Program through the National Research Foundation (NRF), which is funded by the Korean Ministry of Science, ICT & Future Planning (NRF-2021M3E5D9021368). This research was also supported by grants (19181MFDS424, 21181MFDS294) from Ministry of Food and Drug Safety in 2020 and 2021."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025