Reduced d-serine levels drive enhanced non-ionotropic NMDA receptor signaling and destabilization of dendritic spines in a mouse model for studying schizophrenia.

Publication Year: 2022

DOI:
10.1016/j.nbd.2022.105772

PMCID:
PMC9352378

PMID:
35605760

Journal Information

Full Title: Neurobiol Dis

Abbreviation: Neurobiol Dis

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Neurology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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50.0% Transparent
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"Declaration of Competing Interest: The authors declare no competing interests."

Evidence found in paper:

"This work was supported by the NIH (R01 NS062736, R01 MH117130 T32 GM007377, T32 MH112507, T32 GM099608), an ARCS scholar award (D.K.P.), and the Deutsche Forschungsgemeinschaft Walter Benjamin project 468470832 (M.A.). We thank Joseph Coyle for the SRKO mice; Johannes Hell for CaMKIIα, GluN1, GluN2B, GluN2A, GluA1, and Cav1.2 antibodies; Julie Culp, Jennifer Jahncke, and Lorenzo Tom for support with experiments and analysis; and Joseph Coyle, Darrick Balu, Johannes Hell, and Scott Cameron for critical input."

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Last Updated: Aug 05, 2025