Effect of Somatosensory Interaction Transcutaneous Electrical Acupoint Stimulation on Cancer-related Fatigue and Immunity: A Randomized Controlled Trial.

"The authors declare no conflicts of interest."

"This research was supported by Zhejiang Provincial Basic Public Welfare Research Project under Grant No. LGF20H290002 and Traditional Chinese Medicine Scientific Research Fund Project of Zhejiang Province under Grant No. 2022ZB016."

"This study was a randomized controlled trial design. The study protocol had been registered in China Clinical Trial Registration Center with registration number: ChiCTR2100045655. The study had been approved by the Ethics Committee of Zhejiang Provincial People’s Hospital (approval number: 2021QT133). Written informed consents had been obtained from all the participants. Methods:: The study protocol had been registered in China Clinical Trial Registration Center with registration number: ChiCTR2100045655. CRF patients were equally divided into SI-TEAS Group, Acupressure Group and Sham Acupressure Group to receive SI-TEAS, acupressure and sham acupressure treatments 5 times a week. The fatigue levels of patients in the 3 groups were measured by the Piper Fatigue Scale during the baseline period and after 4 and 8 weeks (of treatment). The cell immunity of these patients was determined by detecting the T-lymphocyte subsets and NK cells."