<i>M</i> <i>ycobacterium tuberculosis</i>-specific CD4 T-cell scoring discriminates tuberculosis infection from disease.

"Conflict of interest: A. Scheffold and P. Bacher are advisors to Miltenyi Biotec who own IP rights on the use of CD154 for antigen-specific T-cell detection. A. Scheffold, C. Meisel, H-D. Volk, P. Bacher, T. Meyer and A. Mantei are listed as inventors in a patent (10 2018 131 696.8) that has been issued and a patent (PCT/EP2019/084392) that is pending on the discrimination of TB infection and TB disease using the method described herein. The remaining authors declare no competing financial interests."

"Support statement: This study was supported by research funding from Labor Berlin – Charité Vivantes Services GmbH and by a research grant from the German Federal Ministry of Education and Science (BMBF) (Project InfectControl 2020 DIAT (Fkz 03ZZ0827A)) to A. Scheffold. Funding information for this article has been deposited with the Crossref Funder Registry."