Complement C3 deficiency alleviates alkylation-induced retinal degeneration in mice.

"Declarations Ethics approval and consent to participateAll animal protocols were conducted according to the ARVO Statement for the Use of Animals in Ophthalmic and Vision Research. The animal protocol was approved by the Institutional Animal Care and Use Committee of the General Hospital of Chinese People’s Liberation Army and the Academy of Military Medical Sciences (ID number: 307-ky-090). C57BL/6J mice were provided by Charles River Laboratories (Beijing, China). C3 KO mice were kindly gifted by Professor Yusen Zhou (State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China). Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This work was supported by grants from the National Key Research and Development Program of China (2018YFA0107303) and the National Natural Science Foundation of China (82070990)."