Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride-rich lipoprotein metabolism.

"microarray data from the ad-hapof experiment are deposited in geo under the record gse203290."

"CONFLICTS OF INTEREST All authors have no conflicts of interest to declare."

"FUNDING INFORMATION This work was supported by the Fondation pour la Recherche Médicale (FDT202001010946 to Audrey Deprince), the FP7 “RESOLVE” (Grant ID: 305707 to Joel T. Haas, Bart Staels, An Verrijken, Sven Francque), the European Genomic Institute for Diabetes (ANR‐10‐LABX‐0046 to François Pattou and Bart Staels), the Agence Nationale de la Recherche PreciNASH (ANR‐16‐RHUS‐0006 to François Pattou and Bart Staels), and DeCodeNASH (ANR‐20‐CE14‐0034 to Joel T. Haas) projects. Audrey Deprince was supported by a PhD fellowship from Ministère de l'Education Nationale et de la Technologie (France); the Innovative Medicines Initiative 2 ‐ grant agreement no. 875534 (Stratification of Obesity Phenotypes to Optimize Future Obesity Therapy—SOPHIA to François Pattou. Joel T. Haas was supported by an European Molecular Biology Organization Long Term Fellowship (ALTF277‐2014). Bart Staels is a recipient of a European Research Council Advanced Grant (no. 694717). Sven Francque received a senior clinical research fellowship from the Research Foundation Flanders (1802154N). The project was also partially funded by the Antwerp University (GOA 2018, ID36572), the Association Française pour l'Etude du Foie (AFEF AAP2019) and by the European Commission: HEPADIP (Contract LSHM‐CT‐2005‐018734). The work is supported by the Netherlands CardioVascular Research Initiative: “the Dutch Heart Foundation, Dutch Federation of University Medical Centers, the Netherlands Organization for Health Research and Development and the Royal Netherlands Academy of Sciences” [CVON2017‐2020; Acronym Genius2 to Jan Albert Kuivenhoven]. Jan Albert Kuivenhoven is Established Investigator of the Netherlands Heart Foundation [2015T068]. Funding information Agence Nationale de la Recherche, Grant/ Award Number: ANR-16- RHUS- 0006 and ANR-20- CE14- 0034; European Genomic Institute for Diabetes, Grant/Award Number: ANR-10- LABX- 0046; European Molecular Biology Organization, Grant/ Award Number: ALTF277-2014; Fondation pour la Recherche Médicale, Grant/ Award Number: FDT202001010946; Fonds Wetenschappelijk Onderzoek, Grant/Award Number: 1802154N; H2020 European Research Council, Grant/ Award Number: 694717; Innovative Medicines Initiative, Grant/Award Number: SOPHIA-875534; Ministère de l'Éducation Nationale; Seventh Framework Programme, Grant/Award Number: 305707 and LSHM-CT- 2005- 018734; the Netherlands CardioVascular Research Initiative, Grant/Award Number: CVON2017-2020; the Netherlands Heart Foundation, Grant/Award Number: 2015T068; Universitair Ziekenhuis Antwerpen, Grant/Award Number: GOA 2018 and ID36572; AFEF (Association Française pour l’Étude du Foie), Grant/ Award Number: AAP2019"