Children included in randomised controlled trials of biologics in inflammatory bowel diseases do not represent the real-world patient mix.

"Declaration of personal interests: OA: None. GPM: Received last 3 years consultation fee, research grant, royalties or honorarium from Nestle Health Sciences, Abbvie, Janssen and Lilly. VMNL: Received last 3 years consultation fee, research grant, royalties, or honorarium from Abbvie. EOM: None. OL: None. RLT: None. GF: Received last 3 years consultation fee from Abbvie and Lill. ES: None. JMDC: None. RS: Received last 3 years research grants from Janssen and Pfizer. MA: Received last 3 years consultation fee, research grant, royalties, or honorarium from Abbvie and Pfizer. RKR: Received last 3 years consultation fee, research grant, royalties, or honorarium from Nestle Health Sciences, Janssen, Tillots, Celltrion & Abbvie. DT: Received last 3 years consultation fee, research grant, royalties, or honorarium from Janssen, Pfizer, Hospital for Sick Children, Ferring, Abbvie, Takeda, Atlantic Health, Shire, Celgene, Lilly, Roche, Thermo Fisher, BMS. Approval: All authors approved the final version of the manuscript."