Diagnostic Ability of Volatile Organic Compounds in Digestive Cancer: A Systematic Review With Meta-Analysis.

"Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article."

"Funding: The author(s) received no financial support for the research, authorship, and/or publication of this article."

"This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The protocol of this study is documented on PROSPERO (CRD42021260039). Two authors independently searched the term combination of VOCs and targeted cancer in PubMed and Ovid-Medline (updated to May 25, 2020). The details of search strategy are described in Supplemental File S2. Conclusions:: Volatile organic compounds have potential role in diagnosing GI cancer with comparatively high sensitivity, specificity, and AUC (PROSPERO registration number: CRD42021260039)."