Weighted Zernike defocus coefficient of treatment zone is a meaningful indicator for myopia control efficacy of Ortho-K lenses.

"Declarations Ethics approval and consent to participateThis study followed the tenets of the Declaration of Helsinki and was approved by the Medical Ethics Committee of Peking University People’s Hospital (No. 2018PHA018-001). Consent for publicationNot applicable. Competing interestsJia Qu is the editor in chief of the journal. The other authors have no competing interests. Competing interests Jia Qu is the editor in chief of the journal. The other authors have no competing interests."

"Funding This work was supported by the National Natural Science Foundation of China (Grant Nos. 82171092, 81870684), National Key R&D Program of China (Grant No. 2020YFC2008200). The funders had no role in the study design, data collection and analysis, decision to publish or preparation of the paper."