3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk.

"availability of data and materials the treg atac-seq and hi-c datasets analysed during the current study are available in the european nucleotide archive (ena) repository (prjeb39882).; published data: foxp3 chip-chip data used during the current study are available on gene expression omnibus (accession no gse20995) [ 31 ].; treg and th1 rna-seq data used during the current study are available on european nucleotide archive (accession no err1198158 and err1198159) [ 41 ]. availability of data and materials the treg atac-seq and hi-c datasets analysed during the current study are available in the european nucleotide archive (ena) repository (prjeb39882"

"source code for 3dfaacts-snp workflow and related in-house scripts are available in github ( https://github com/ningbioinfostruggling/3dfaacts-snp )."

"Declarations Ethics approval and consent to participateCord blood used in this study was obtained with approval from the donor and the Children’s, Youth and Women’s Health Service Research Ethics Committee (HREC1596 and HREC 19/wchn/65 from the Women’s and Children’s Health Network Human Ethics committee). Buffy Coats were obtained from the Australian Red Cross (Material Supply Deed 19-03SA-02). Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This research was supported by a 2017 National Health and Medical Research Council (NHMRC) project Grant (#399123, #565314 and 1120543). Dr Sadlon and Professor Barry are supported by a Women’s and Children’s Hospital Foundation Grant. Dr James Breen is supported by the James & Diana Ramsay Foundation."