High-level dolutegravir resistance can emerge rapidly from few variants and spread by recombination: implications for integrase strand transfer inhibitor salvage therapy.

Authors:
Huik K; Hill S; George J; Pau A; Kuriakose S and 9 more

Journal:
AIDS

Publication Year: 2022

DOI:
10.1097/QAD.0000000000003288

PMCID:
PMC9594130

PMID:
35848510

Journal Information

Full Title: AIDS

Abbreviation: AIDS

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Acquired Immunodeficiency Syndrome

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Core Indicators
Evidence found in paper:

"sequences are available at genbank (op160627-op160877)."

Code Sharing
Evidence found in paper:

"Conflicts of interest There are no conflicts of interest."

Evidence found in paper:

"Funding source: These studies were supported by Intramural Research Program of the NIH by funding to F. Maldarelli: ZIABC010819."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
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Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025