Distinct immune-effector and metabolic profile of CD8⁺ T cells in patients with autoimmune polyarthritis induced by therapy with immune checkpoint inhibitors.

"Competing interests: KB: Consultancy and/or speaker fees and/or travel reimbursements: Abbvie, Bristol Myers Squibb (BMS), Gilead/Galapagos, Janssen, Merck Sharp & Dohme (MSD), Mundipharma, Novartis, Pfizer, Roche, Viatris, UCB. Scientific support: Medical Faculty of University of Heidelberg, Rheumaliga Baden-Württemberg e.V., AbbVie, Novartis. MMSC: Scientific support: Novartis, Pfizer. JCH: honoraria: BMS, MSD, Novartis, Roche, Pierre Fabre, Sanofi, Almirall; consultant or advisory role: MSD, Pierre Fabre, Sunpharma; Scientific support: BMS; Travel support: Pierre Fabre. PC: honoraria: Roche, Takeda, Gilead, AstraZeneca, Novartis; scientific support: Roche, Takeda, Amgen, Merck, AstraZeneca, Novartis; travel support: AstraZeneca, Merck, Janssen, Daiichi Sankyo, Takeda, Novartis, Elli Lilly; data safety monitoring and/or advisory board: Pfizer, Chugai, Boehringer Ingelheim, Roche. JG: honoraria: Galapagos; travel support: Elli Lilly. HML: Scientific funding: Abbvie, Novartis, Pfizer, Roche; consulting fees and honoraria: Abbvie, AstraZeneca, Actelion, Amgen, Bayer Vital, Boehringer Ingelheim, BMS, Celgene, GlaxoSmithKline (GSK), Galapagos, Janssen, Elli Lilly, Medac, MSD, Novartis, Pfizer, Roche, Sanofi, UCB; travel support: Abbvie, AstraZeneca, Boehriner Ingelheim, BMS, Celgene, GSK, Gilead, Janssen, Elli Lilly, MSD, Novartis, Pfizer, Roche, Sanofi, UCB; data safety monitoring and/or advisory board: Abbvie, AstraZeneca, Amgen, Boehriner Ingelheim, BMS, Celgene, GSK, Gilead, Janssen, Elli Lilly, Medac, MSD, Novartis, Pfizer, Roche, Sanofi, UCB"

"Funding: This work was funded by the unrestricted investigator-initiated grant WI245418 from Pfizer Pharma GmbH to MMSC. The funding body did not have any influence on the study design, nor on the data acquisition and analysis and interpretation. FV Kraus was supported by an Add-On Fellowship of the Joachim Herz Foundation."