An interim oral appliance as a screening tool during drug-induced sleep endoscopy to predict treatment success with a mandibular advancement device for obstructive sleep apnea.

"Declarations Ethics approvalAll procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (METC) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study was approved by the national medical ethical committee (METC) and by the board of directors (IRB) of OLVG hospital (WO18.168). Consent to participateInformed consent was obtained from all individual participants included in the study. Conflicts of interestDr. A. Hoekema is medical advisor for Airway Management Inc., SomnoMed, and Zephyr Sleep Technologies.Prof. Dr. F. Lobbezoo receives research grants from Sunstar Suisse SA, SomnoMed, Vivisol-ResMed, Health Holland/TKI, and NWO and is an unpaid member of the academic advisory boards for GrindCare and for Oral Function (Sunstar Suisse SA).Prof. Dr. N. de Vries is member of the Medical Advisory Board of NightBalance, consultant of Philips Healthcare, Nyxoah, and Inspire Medical Systems.All other authors certify that they have no affiliations with, or involvement in, any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript. Conflicts of interest Dr. A. Hoekema is medical advisor for Airway Management Inc., SomnoMed, and Zephyr Sleep Technologies. Prof. Dr. F. Lobbezoo receives research grants from Sunstar Suisse SA, SomnoMed, Vivisol-ResMed, Health Holland/TKI, and NWO and is an unpaid member of the academic advisory boards for GrindCare and for Oral Function (Sunstar Suisse SA). Prof. Dr. N. de Vries is member of the Medical Advisory Board of NightBalance, consultant of Philips Healthcare, Nyxoah, and Inspire Medical Systems. All other authors certify that they have no affiliations with, or involvement in, any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript."

"Funding This study was financially supported by Airway Management Inc."

"Data availability: The data that support the findings of this study are available upon reasonable request.: The study is registered with Netherlands Trial Registers (NL64738.100.18)."