The tyrosine capsid mutations on retrograde adeno-associated virus accelerates gene transduction efficiency.

"Declarations Ethics approval and consent to participateAll experiments were conducted in accordance with The University of Tokyo's Regulations for Animal Experiments and The University of Tokyo's Regulations for the Use of Genetically Modified Organisms. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding AMED-PRIME, JSPS (KAKENHI 19H03541, 19H05029, 20K21458, 21H05176, and 22H02942) to AU; MEXT Grants-in-Aid for Scientific Research on Innovative Areas “Dynamic regulation of brain function by Scrap and Build system” (KAKENHI 16H06456), JSPS (KAKENHI 16H02504), WPI-IRCN, AMED-CREST (22gm1310010h0001), JST-CREST, the Strategic Research Program for Brain Sciences, Toray Foundation, Naito Foundation, Takeda Science Foundation, and Uehara Memorial Foundation to KE."