Bullous pemphigoid anti-BP180-NC16A autoantibody reactivity in healthy individuals is associated with marked hypovitaminosis D and Th2-like cytokine predominance.

"Declarations Conflict of interestThere are no competing conflicts of interest. Ethical approvalUse of human biological material was approved by the ethics committee of the University of Lübeck, and written informed consents were obtained in accordance with the Declaration of Helsinki. Conflict of interest There are no competing conflicts of interest."

"This study was supported by the Cluster of Excellence “Precision Medicine in Chronic Inflammation” (EXC 2167), the Research Training Group “Modulation of Autoimmunity” (GRK 1727), both from the Deutsche Forschungsgemeinschaft, the Schleswig-Holstein Excellence-Chair Program from the State of Schleswig-Holstein, and the Polish National Science Centre (NCN), grant no. 2017/25/B/NZ6/00305 and 2020/39/B/NZ6/00357. We are grateful to Astrid Fischer and Sylva Dürkop (Lübeck) for excellent technical assistance."