Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis.

"whole-genome shotgun sequencing data are available in the genome sequence archive (gsa) section of the national genomics data center (project accession number cra004348) 16s rrna gene sequencing data are available in the genome sequence archive (gsa) section of the national genomics data center (project accession number cra005811).; plasma metabolomic data are available in the metabolights (project accession number mtbls5297). these stage-specific altered species had the potential to serve as the targets for intervention in a given ra stage 10 1136/ard-2022-222871 supp2 supplementary data 10 1136/ard-2022-222871 supp3 supplementary data next we sought to detect the microbial dysfunction across stages of ra."

"Competing interests: None declared."

"Funding: This work was partially funded by the National Natural Science Foundation of China (grant numbers 31871334, 82003766, 32071465, and 31671374), the Academic Promotion Programme of Shandong First Medical University (grant number 2019LJ001) and the Key Research and Development project of Shandong Province (grant number 2021ZDSYS27)."