Effects of Different Montages of Transcranial Direct Current Stimulation on Haemodynamic Responses and Motor Performance in Acute Stroke: A Randomized Controlled Trial.

"The authors have no conflicts of interest to declare."

"This work was supported by the National Research Council of Thailand (NRCT) (grant number 2562/11005), the Thailand Science Research and Innovation (Program Management Unit: PMU-P5 Frontier Research) (grant number 2563/6007 Re-Submit) and Mahidol University. P. Jitkaew had a grant from the National Research Council of Thailand (NRCT) (grant number 2562/24415)."

"The study protocol is registered at ClinicalTrials.gov (NCT04051658). The participants provided written informed consent before the study commenced, and the study was approved by the ethics committee of the Faculty of Medicine at Siriraj Hospital. This study was a double-blind (participants, assessor) randomized controlled trial. Participants were allocated randomly to the anodal group (n = 21), cathodal group (n = 20), dual group (n = 20), or sham group (n = 21) by a third party. Match-paired design was used to match age (± 5 years), lesions, and motor subscale from the NIHSS (upper extremities (UE): 0–1, 2, 3–4 or lower extremities (LE): 0–1, 2). Randomization was performed using sealed envelopes marked “active,” “cathodal,” “dual,” or “sham” when it was necessary to start a new pair. The assessments were performed at the baseline (pre-), immediately after day-5 intervention (post-), and at 1-month follow-up ()."