IRES-mediated Wnt2 translation in apoptotic neurons triggers astrocyte dedifferentiation.

Authors:
Fan H; Yang J; Zhang K; Xing J; Guo B and 17 more

Journal:
NPJ Regen Med

Publication Year: 2022

DOI:
10.1038/s41536-022-00248-1

PMCID:
PMC9440034

PMID:
36056026

Journal Information

Full Title: NPJ Regen Med

Abbreviation: NPJ Regen Med

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Engineering, Biomedical

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"Competing interests The authors declare no competing interests."

Evidence found in paper:

"This work was supported by grants from the National Natural Science Foundation of China (Grant code: 82171346, 31970907) to Y.W., National Natural Science Foundation of China (Grant code: 81730035) to S.W., the National Key R&D program of China (2017YFA0104002) and Shanghai Municipal Science and Technology Major Project (No. 2018SHZDZX01) to Y.-Q.D., National Natural Science Foundation of China (Grant code: 82171471) to H.F., National Natural Science Foundation of China (Grant code: 82171269) and Beijing Nova Program (Grant code: Z201100006820076) to J.Y., National Natural Science Foundation of China (Grant code: 31771371) to J.D. J.D. is supported by grant Xi’an Jiaotong University “Young Talent Scholar Program”.The authors thank Prof. Yi Eve Sun (University of California, Los Angeles) for critical reading and constructive comments on this manuscript, Dr. Roel Nusse (Stanford University) for the lentiviral vectors of EbC and EdTC, Dr. Deyang Li for preparing pLenti-Wnt2 construct, Dr. Lin Xu for his help in monkey experiments, Dr. Gang Li for his help in human tissue study and Drs Xunyuan Liu, Yuanhang Pan, Xiufen Zhang, Dong Wang, Chen Wang, Yahui Shen, Xinyu Liu and Junjia Shan for mice maintenance and genotyping."

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Last Updated: Aug 05, 2025