Somatic copy number alteration and fragmentation analysis in circulating tumor DNA for cancer screening and treatment monitoring in colorectal cancer patients.

"availability of data and materials the sequence data have been deposited at the european genome-phenome archive (ega) under accession number egas00001006490 . availability of data and materials the sequence data have been deposited at the european genome-phenome archive (ega) under accession number egas00001006490"

"Declarations Ethics approval and consent to participateThe study was approved by the ethics commission of the Bavarian Medical Association (No. 17059) and is registered with the German registry for clinical trials (trial registration ID: DRKS00012890). All participants provided informed written consent prior to blood and tissue specimen collection. The study was performed in accordance with the Declaration of Helsinki. Consent for publicationAll participants provided informed written consent to the publication of their data. This manuscript has been read and approved for publication by all named authors. Competing interestsThe authors declare no potential conflicts of interest. Competing interests The authors declare no potential conflicts of interest."

"Funding The authors received no specific funding for this work."

"Trial registration DRKS00012890."