c-Rel-dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis.

Authors:
Leslie J; Hunter JE; Collins A; Rushton A; Russell LG and 13 more

Journal:
Hepatology

Publication Year: 2023

DOI:
10.1002/hep.32781

PMCID:
PMC10521790

PMID:
36089330

Journal Information

Full Title: Hepatology

Abbreviation: Hepatology

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Gastroenterology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"CONFLICTS OF INTEREST Derek A. Mann owns stock in, is employed by, received grants from, and owns intellectual property rights in FibroFind Ltd. Jack Leslie owns stock in Fibrofind Ltd. Fiona Oakley owns stock in, received grants from, and is employed by FibroFind Ltd. She owns stock in FibroFind IP Ltd and FF Estates Ltd."

Evidence found in paper:

"FUNDING INFORMATION This work was funded by a UK Medical Research Council PhD studentship to J.L.; program grants MR/K0019494/1 to D.A.M, and F.O.; and grant MR/R023026/1 to D.A.M, and F.O. A CRUK program grant, reference C18342/A23390, supports J.L. and D.A.M. H.L.R, D.A.M., and F.O. received Cancer Research UK funding through the HUNTER HCC expediter network award (C9380/A18084). The cross‐council Lifelong Health and Wellbeing initiative, funded by the Medical research Council (award reference i L016354), funds D.A.M and F.O. J.E.H. and N.D.P. were supported by Cancer Research UK grant C1443/A22095. M.Y.W.Z. was supported by a personal award from the Newton‐Mosharafa Fund and is currently funded by Newton Prize 2020. A.C. is funded by the W.E. Harker Foundation. D.G. is funded by the Newcastle CRUK Clinical Academic Training Programme. Funding information Cancer Research UK, Grant/Award Number: C1443/A22095, C18342/A23390, C9380/A18084 and Clinical Academic Training Programme to DG; Medical Research Council, Grant/Award Number: MR/K0019494/1, MR/R023026/1 and i L016354; Newton Fund, Grant/ Award Number: Newton prize 2020; Newton-Mosharafa Fund; W. E. Harker Foundation, Grant/Award Number: PhD studentship"

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Last Updated: Aug 05, 2025