Reference Ranges for NT-proBNP (N-Terminal Pro-B-Type Natriuretic Peptide) and Risk Factors for Higher NT-proBNP Concentrations in a Large General Population Cohort.

"Disclosures Dr Welsh reports grant income from Roche Diagnostics within this work and grant income from AstraZeneca, Boehringer Ingelheim, and Novartis, and speaker fees from Novo Nordisk, outside the submitted work. Dr Sattar has received grant and personal fees from AstraZeneca, Boehringer Ingelheim, and Novartis; grant from Roche Diagnostics; and personal fees from Abbott Laboratories‚ Afimmune, Amgen, Eli Lilly, Hanmi Pharmaceuticals, Merck Sharp & Dohme, Novo Nordisk, Pfizer, and Sanofi outside the submitted work. Dr Januzzi is a Trustee of the American College of Cardiology; is a board member of Imbria Pharmaceuticals; has received grant support from Abbott Diagnostics, Applied Therapeutics, Innolife, and Novartis; has received consulting income from Abbott Diagnostics, Boehringer Ingelheim, Janssen, Novartis, and Roche Diagnostics; and participates in clinical end point committees/data safety monitoring boards for AbbVie, Siemens, Takeda, and Vifor. Dr McMurray reports payments to his employer, University of Glasgow, for work on clinical trials, consulting, lecturing, and other activities from Alnylam, Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Bristol Myers Squibb, Cardurion, Cytokinetics, Dal-Cor, GlaxoSmithKline, Ionis, KBP Biosciences, Novartis, Pfizer, and Theracos, as well as personal lecture fees from Abbott, Hikma, Sun Pharmaceuticals, and Servier. Dr Mills has received honoraria from Abbott Diagnostics, Siemens Healthineers, and Singulex, and the University of Edinburgh has received research grants from Abbott Diagnostics and Siemens Healthineers. All other authors declare no conflicts."

"Sources of Funding Roche Diagnostics supported this study through provision of free reagents and a grant. Generation Scotland received support from the Chief Scientist Office of the Scottish Government Health Directorates (CZD/16/6) and the Scottish Funding Council (HR03006). Dr Mills is supported by a British Heart Foundation Senior Clinical Research Fellowship (FS/16/14/32023). Dr Januzzi is supported in part by the Hutter Family Professorship Chair. Drs McMurray and Sattar are supported by British Heart Foundation Centre of Research Excellence Grant RE/18/6/34217. D.M. Kimenai was supported by Health Data Research UK, which receives its funding from HDR UK Ltd (HDR-5012) funded by the UK Medical Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, Department of Health and Social Care (England), Chief Scientist Office of the Scottish Government Health and Social Care Directorates, Health and Social Care Research and Development Division (Welsh Government), Public Health Agency (Northern Ireland), British Heart Foundation‚ and the Wellcome Trust. The funders had no role in the design and conduct of the study, in the collection, analysis, and interpretation of the data, and in the preparation, review, or approval of the article."