Polyclonal evolution of Fanconi anemia to MDS and AML revealed at single cell resolution.

"our high-throughput datasets have been deposited to public gsa-human repository with the accession number [hra002517].; our high-throughput datasets have been deposited to public gsa-human repository with the accession number [hra002517]."

"Declarations Ethics approval and consent to participateAll patients provided written consent on a protocol approved by the Clinical Research Ethics Committee of Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences (HG2021007-EC-1). Consent for publicationThe parents of all patients gave consent for the data to be published. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This work was partially supported by the National Key Research and Development Program of China (2018YFA0107801, 2020YFE0203000, 2019YFA0110803 and 2021YFA1100300); the National Natural Science Foundation of China (82170135, 81500156, 32025006 and 31871266); the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences, CIFMS (2021-I2M-1–040 and 2017-I2M-3–015); Haihe Laboratory of Cell Ecosystem (HH22KYZX0037)."