GluN2A-Selective NMDA Receptor Antagonists: Mimicking the U-Shaped Bioactive Conformation of TCN-201 by a [2.2]Paracyclophane System.

Authors:
Steigerwald R; Chou TH; Furukawa H; Wünsch B.

Journal:
ChemMedChem

Publication Year: 2022

DOI:
10.1002/cmdc.202200484

PMCID:
PMC9828697

PMID:
36169098

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Journal Information

Full Title: ChemMedChem

Abbreviation: ChemMedChem

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Pharmacology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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"Conflict of interest The authors declare no conflicts of interest."

Evidence found in paper:

"This work was supported by the Research Training Group “Chemical biology of ion channels (Chembion)” funded by the Deutsche Forschungsgemeinschaft (DFG), which is gratefully acknowledged. We would like to thank Dr. Max Epstein for helpful discussions regarding the docking studies. HF thanks NIH NS11745, MH085926, Austin's purpose, Robertson funds at Cold Spring Harbor Laboratory, Doug Fox Alzheimer's fund, Heartfelt Wing Alzheimer's fund, and the Gertrude and Louis Feil Family Trust for financial support. Open Access funding enabled and organized by Projekt DEAL."

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Last Updated: Aug 05, 2025