Automated urinary sediment detection for Fabry disease using deep-learning algorithms.

Authors:
Uryu H; Migita O; Ozawa M; Kamijo C; Aoto S and 5 more

Journal:
Mol Genet Metab Rep

Publication Year: 2022

DOI:
10.1016/j.ymgmr.2022.100921

PMCID:
PMC9523392

PMID:
36186840

Journal Information

Full Title: Mol Genet Metab Rep

Abbreviation: Mol Genet Metab Rep

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics & Heredity

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
5/6
83.3% Transparent
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Evidence found in paper:

"to detect the area based on which the models made their judgment we have visualized the heatmaps of the class activation for each segmented image 2 6 mann-whitney u tests were used to compare aucs between each group and analyses were performed using the scipy scikit-learn and keras/tensorflow python packages p < 05 was considered statistically significant 2 7 the image data were blinded and analyzed by h u the entire code is open to the public in github ( https://github com/huryu/dl_fabry ) 2 8 the datasets generated and/or analyzed during the current study are available from the corresponding author upon reasonable request 3 three fabry patients whose diagnosis was definitely confirmed were enrolled in this study as disease-positive cases."

Evidence found in paper:

"our models are already submitted in https://github com/huryu/dl_fabry ."

Evidence found in paper:

"Declaration of Competing Interest All authors have no conflict of interest to declare."

Evidence found in paper:

"Funding This study was supported by the Research & Development grant from the 10.13039/100007786National Center for Child Health and Development (Grant 30-37)."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025