Cardiovascular concentration-effect relationships of amodiaquine and its metabolite desethylamodiaquine: Clinical and preclinical studies.

"COMPETING INTERESTS X.H.S.C. is an NIHR Academic Clinical Lecturer in Infectious Diseases at the University of Oxford previously supported by the Medical Research Council of the United Kingdom (MR/N013468/1) and the Jill and Herbert Hunt Travelling Scholarship of the University of Oxford. R.A.C. is a postdoctoral scientist funded by the Wellcome Trust and Royal Society (109371/Z/15/Z). R.A.B.B. is a Senior Research Fellow of Linacre College funded by a Sir Henry Dale Wellcome Trust and Royal Society Fellowship (109371/Z/15/Z) and acknowledges support from the British Heart Foundation (PG/18/4/33521), the Returning Carers' Fund, Medical Sciences Division, University of Oxford, and the Oxford British Heart Foundation Centre for Research Excellence. N.J.W. is a Wellcome Trust Principal Research Fellow (107886/Z/15/Z) and is a recipient of the Bill and Melinda Gates Foundation award (OPP1132628). The Mahidol‐Oxford Tropical Medicine Research Unit research programme is supported by the Wellcome Trust (106698/Z/14/Z). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript."

"Funding information Wellcome Trust, Grant/Award Numbers: 106698/Z/14/Z, 107886/Z/15/Z, 109371/Z/15/Z, 106698/Z/14/; Medical Research Council, Grant/Award Number: MR/N013468/1; Jill and Herbert Hunt Travelling Scholarship; Royal Society; British Heart Foundation, Grant/Award Number: PG/18/4/33521; Returning Carers' Fund, Medical Sciences Division, University of Oxford; Oxford British Heart Foundation Centre for Research Excellence; Bill and Melinda Gates Foundation, Grant/Award Number: OPP1132628"