Non-REM sleep with hypertonia in Parkinsonian Spectrum Disorders: A pilot investigation.

"Declaration of competing interest As shareholders in Advanced Brain Monitoring, Inc. Mr. Levendowski, Ms. Berka and Dr. Westbrook would financially benefit if the SP intellectual property was acquired by a third party. Dr. Boeve has served as an investigator for clinical trials sponsored by Biogen, Alector, and EIP Pharma. He receives royalties from the publication of a book entitled Behavioral Neurology Of Dementia (Cambridge Medicine, 2009, 2017). He serves on the Scientific Advisory Board of the Tau Consortium. Dr. Salat is a consultant to Cyclerion and Amylyx, has a financial interest in Niji Corp and has served as an investigator on research sponsored by Renew Research. Dr. Lee-Iannotti serves as a paid advisor to and speaker for Jazz Pharmaceuticals. Dr Shprecher received research support from the Arizona Alzheimer’s Consortium, Abbvie, Acadia, Aptinyx, Axovant, Biogen, Eisai, Eli Lilly, Enterin, Neurocrine, Michael J Fox Foundation, NIH, Nuvelution and Teva; consultant fees from Amneal, Forensis and Neurocrine; speaker honoraria from Acorda, Amneal, Intermountain Healthcare, Neurocrine, Sunovion, Teva and US World Meds. Dr. Mazeika serves as the Medical Director of Advanced Brain Monitoring, Inc. None of the other authors reported financial conflicts."

"The authors recognize Vladislav Velimirovic for his assistance in implementing the NRH algorithms in the Sleep Profiler software, Elise Angel, Sarah Payne, Greg Rupp, Marissa McConnell, Jared Poole and Kefron McCaw for their assistance with data acquisition, and David P. Salmon and Doug Galasko for their expertise in recruitment of San Diego participants with AD and MCI. Mr. Levendowski, Dr. Westbrook, and Ms. Berka were supported by the National Institute on Aging-National Institute of Health (NIA-NIH) (R44AG050326 and R44AG054256). Dr. Boeve receives research support from the NIA-NIH (AG062677, NS100620, AG056639), the Mayo Clinic Dorothy and Harry T. Mangurian Jr. Lewy Body Dementia Program, the Little Family Foundation, and the Turner Family Foundation. Dr. Neylan, Dr. Walsh, and Ms. Yack were supported by NIA-NIH grant RO1 AG060477 and the Rainwater Charitable Foundation. Dr. Hamilton and her staff were supported by NIA-NIH grants R44AG050326, R44AG054256 and P50AG005131. Dr. Shprecher received support from the Arizona Alzheimer’s Consortium. Dr. Tsuang was supported by NIA-NIH grant R21AG064271. Dr. St. Louis received research support from the NIH, National Center for Research Resources and the National Center for Advancing Translational Sciences grant UL1 RR024150-01, and by NIA-NIH R34AG056639 (NAPS). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Daniel J. Levendowski : Formal analysis, data curation, investigation, software, validation, writing - original draft. Christine M. Walsh : Funding acquisition, methodology, project administration, writing - review & editing. Bradley F. Boeve : Investigation, methodology, writing - review & editing. Debby Tsuang : Funding acquisition, methodology, project administration, writing - review & editing. Joanne M. Hamilton : Funding acquisition, project administration, writing - review & editing. David Salat: Resources, project administration, supervision. Joyce K. Lee-Iannotti : Project administration, resources supervision. David Shprecher : Funding acquisition, resources, writing - review & editing. Chris Berka : Funding acquisition, project administration, writing - review & editing. Philip R. Westbrook : Writing - review & editing. Gandis Mazeika : Writing - review & editing. Leslie Yack : Project administration, supervision. Sarah Payne : Project administration. Paul C. Timm : Formal analysis, Project administration. Thomas C. Neylan : Conceptualization, methodology, visualization, writing - review & editing. Erik K. St. Louis : Conceptualization, investigation, methodology, writing - original draft."