Randomised clinical trial: comparison of tegoprazan and lansoprazole as maintenance therapy for healed mild erosive oesophagitis.

"Declaration of personal interests : The authors thank all the investigators who contributed to this study. Statistical analysis was supported by Heechan Lee, Heehyun Kim, Jihyeon Kim, Min Ja Kang and Bong Tae Kim who are employees of HK inno.N Corp., Seoul, Korea."

"FUNDING INFORMATION This study was funded in full by HK inno.N Corp., Seoul, Korea."

"This was a multi‐centre, randomised, double‐blind, actively controlled, phase 3 study designed to assess the non‐inferiority of tegoprazan 25 mg to lansoprazole 15 mg as maintenance therapy in Korean patients with healed EE. The study protocol was reviewed and approved by the Institutional Review Boards of 33 institutes. This study was performed in accordance with the Declaration of Helsinki and the International Congress on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use for Good Clinical Practice guidelines. Written informed consent was obtained from all subjects prior to any study‐related procedure. This study was registered at ClinicalTrials.gov (identifier number: NCT04022096; Study title: Study to confirm the safety and efficacy of tegoprazan in patients with healed erosive oesophagitis)."