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"Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

"This work was supported by the EPSRC programme for next generation molecular imaging and therapy with radionuclides (EP/S032789/1), the Wellcome EPSRC Centre for Medical Engineering at KCL [grant number WT 203148/Z/16/Z], a CRUK Multidisciplinary Project Award [grant number C48390/A21153], the King’s College London & Imperial College London EPSRC Centre for Doctoral Training in Smart Medical Imaging [EP/S022104/1], the KCL/UCL Comprehensive Cancer Imaging Centre funded by CRUK and EPSRC in association with the MRC and DoH (England), the Medical Research Council Confidence in Concepts scheme, the Experimental Cancer Medicine Centre at KCL, the KHP/KCL CRUK Cancer Centre, a Wellcome Trust Multiuser Equipment Grant: A multiuser radioanalytical facility for molecular imaging and radionuclide therapy research [212885/Z/18/Z], the National Institute for Health Research (NIHR) Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust and KCL [grant number IS-BRC-1215-20006], the MRC Doctoral Training Programme, the Research England Confidence in Collaboration scheme. Magda Swedrowska is an employee of AstraZeneca. Francis Man is an employee of GE Healthcare. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, the Department of Health, AstraZeneca or GE Healthcare."