Tumor-derived OBP2A promotes prostate cancer castration resistance.

Authors:
Jeong JH; Zhong S; Li F; Huang C; Chen X and 6 more

Journal:
J Exp Med

Publication Year: 2022

DOI:
10.1084/jem.20211546

PMCID:
PMC9789742

PMID:
36547668

Journal Information

Full Title: J Exp Med

Abbreviation: J Exp Med

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Allergy and Immunology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"the rna-seq data was deposited in the gene expression omnibus under accession no gse208321 . to test this possibility we linked ?-pinene to dox to produce dox-pin ( fig 6 a and fig m1 in data s1 ).; we linked ?-pinene to dtx to produce dtx-pin ( fig 6 e and fig m2 in data s1 ).; the detail of the synthesis can be found in data s1 .; data s1 shows synthesis details.; data s1 shows the compound synthesis details."

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"Disclosures: The authors declare no competing interests exist."

Evidence found in paper:

"This work was supported by grants from National Institute of Health (R01CA140956, R01CA197944) and the United States Department of Defense (W81XWH-15-1-0235) to J.-L. Luo, and a postdoctoral trainee fellowship from the Frenchman’s Creek Women For Cancer Research to J.H. Jeong. Author contributions: Conceptualization, J.-H. Jeong, S. Zhong, and J.-L. Luo; Data curation, J.-L. Luo; Formal analysis, J.-H. Jeong and J.-L. Luo; Funding acquisition, J.-H. Jeong and J.-L. Luo; Investigation, J.-H. Jeong, S. Zhong, F. Li, C. Huang, X. Chen, Q. Liu, S. Peng, H. Park, Y.M. Lee, J. Dhillon, and J.-L. Luo; Methodology, J.-H. Jeong, S. Zhong, F. Li, C. Huang, X. Chen, Q. Liu, H. Park, S. Peng, and J.-L. Luo; Project administration, J.-L. Luo; Resources, J. Dhillon and J.-L. Luo; Supervision, J.-L. Luo; Validation, J.-H. Jeong and J.-L. Luo; Visualization, J.-H. Jeong and J.-L. Luo; Writing—original draft, J.-H. Jeong, S. Zhong, F. Li, and J.-L. Luo; Writing—review & editing, J.-H. Jeong, S. Zhong, X. Chen, and J.-L. Luo. All authors have read and approved the manuscript."

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Last Updated: Aug 05, 2025